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 Department of Morbid Anatomy & Histopathology

Introduction

The department of Morbid Anatomy & Histopathology is a bridge between Basic and Clinical Medical Sciences and is actively involved in teaching and research in basic and clinical subjects. The department is offering Ph.D program in Pathology and related specialists.


Dr. Abdul Hannan Nagi
Professor & Head of Department
MBBS (Pb) ,Ph.D (Queen’s) ,MRC Path (London)
FCPS, FCPP ,FRCP (Dublin), FRC Path (London)
E-mail : headpathology@uhs.edu.pk
Dr. Farooq Aziz
Associate Professor
MBBS, M.Phil (Morbid Anatomy & Histopathology)
E-mail : pathologydept@uhs.edu.pk

Mission

Research in Health Sciences has been neglected in the past. Under the umbrella of University of Health Sciences, department is determined to boost research activities in basic and clinical medical sciences. Our mission is to produce Ph.Ds of international standard in collaboration with foreign universities. MOU with university of Texas has already been signed for exchange of graduate students and faculty members.

Areas of Research

Main area of research is Oncological nephropathology & primary muscle disorders.

Topics of Research Projects

Projects Comompleted

  • In vitro Cytotoxity of Chemotherapeutic drugs of mammary carcinoma.
  • Prediction of efficacy of Chemotherapy in Breast Cancer-development of efficacy index.
  • Study of Benign and malignant effusions: Blood Group antigen versus P53.
  • Role of P27 protein (cell cycle Cylin D kinase inhibitor) in chemically induced breast tumours of female Albino rats.
  • Human Papilloma virus in cervical intraepithelial neoplasis and invasive carcinoma.
  • Assessment of HER-2/ neu status by Immuno-histochemical (IHC) method and gene amplification by molecular PCR method in localized /metastatic carcinoma of the breast.
  • Association between Homocytiene level and Myocardial infarction & influence of B vitamin Therapy on Homocytiene levels.
  • Immunohistochemical Detection and correlation of the Histidine Decarboxylase and CYFRA 21-1-(Ck-19) in primary lung cancers.
  • Expression of HER 2/neu and its correlation with the histological grading of colorectal carcinoma.
  • Immunohistochemical expression and correlation of mammaglobin with scarf-bloom Richardson grading system of breast carcinoma.
  • Expression of bcl-2 oncoprotein in uterine leiomyoma as an apoptosis inhibitor.
  • Correlation of estrogen receptor status with the Ki-67 proliferative index in carcinoma of the breast.
  • Study of Ki-67 labeling index with grading and staging colorectal carcinoma.
  • Role of DNA Analysis in sexually assault victims.
  • A morphological study of muscular dystrophies and the role of dystrophin in their diagnosis.
  • Morphological study of placentas in pre-eclampsia anmd eclampsia.
  • Diagnostic role of CD117 in small cell carcinoma of lung.
  • Morphological study of round blue cell tumours of childhood and their classification.
  • Morphology of Hirschsprung’s disease in suction and full thickness rectal biopsies.
  • Keloid, it’s experimental & therapeutic approach (P.hD topic).

Academic Collaboration

In addition to a meaningful interaction with other departments of basic and clinical sciences within UHS and its affiliated colleges and institutions, the department will coordinate and collaborate in training and research with other national biomedical institutions like the Institute of Nuclear Medicine and Oncology Lahore (INMOL) and National Institute of Biotechnology and Genetic Engineering (NIBGE). Linkages are being developed with foreign institutions both for collaborative research and for short term training of personnel in specialized techniques and procedures.

Teaching Activities

The members of our faculty pursue an active involvement in the student recruitment, curricular development, teaching and research. It consists of a dedicated team of individuals with varying interests, duties and responsibilities. Teaching will be based on formal lectures, tutorials, problem based learning, discussions, interactive sessions, seminars, journal club and laboratory training.

Admission

Postgraduate program at UHS in the department of Morbid Anatomy & Histopathology is research training program leading to Ph.D Candidates who are medical/ dental graduate and possess Postgraduate/ higher diploma are eligible for admission in Ph.D program. The department also runs M.Phil leading to Ph.D program for bright fresh graduates/ graduates with teaching/ practical experience.



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