Research Activities
Session 2005-2007 1. Immunohistochemical Expression of Histidine Decarboxylase and Cytokeratin 19 and its correlation with histological grading in primary lung carcinomas by Dr. Nadia Naseem (Awarded Degree) Session 2006 2008 1. Expression of HER 2/neu and its correlation with the histological grading of colorectal carcinomaby Dr. Sadia Anwar (Awarded Degree) 2. Study of Ki-67 labeling index with grading and staging of colorectal carcinoma. By Dr. Uzma Nabi (Awarded Degree) 3. Correlation of Estrogen Receptor expression with the Ki-67 proliferative index in carcinoma of the breast by Dr. Mahwish Hussain (Awarded Degree) 4. Immunohistochemical expression and correlation of Mammaglobin with Scarf-Bloom Richardson grading system of breast carcinoma by Dr. Fakeha Rehman(Awarded Degree) 5. Expression of Bcl-2 oncoprotein in uterine leiomyomata as an apoptosis inhibitor. By Dr. Seema Butt(Awarded Degree) Session 2007 - 2009 1. Diagnostic role of CD117 in small cell carcinoma of lung by Dr. Sobia Sadiq(Awarded Degree) 2. A Morphological Study of Muscular Dystrophies and the Role of Dystrophin in their Diagnosis by Dr. Saira Sajid(Awarded Degree) 3. Morphological Study of Placenta in Pre-eclampsia and Eclampsia by Dr. Maham Akhlaq(Awarded Degree) Session 2008 - 2010 1. Morphological study of Round Blue Cell Tumors of Childhood and their classification. By Dr. Muneeza Khalid (Awarded Degree) 2. Morphology of Hirschsprung�s Disease in suction and full thickness rectal biopsies By Dr. Nausheen Henna (Awarded Degree) Session 2009 � 2011 1. Morphology of Hepatitis C Virus Associated Nephropathy and Expression of Anti HCV-NS3 by Dr. Munazza Chaudhary (Awarded Degree) 2. Morphology of IgA &Henoch-Schonlein Nephropathies-the role of immunofluorescence & iNO by Dr. Atika Masood (Awarded Degree) 3. Expression of p63 and S-100A6 in the Differentiation of KeratinocyticTumours of Skin by Dr. Usman Shams(Awarded Degree) 4. Morphology of Benign Proliferative Breast Lesions in the Mestectomy Specimens. By Dr. SumeraQazi (Awarded Degree) 5. Morphological Study of Renal Lesions in Systemic Lupus Erythematosis by Dr. Fatima Rashid(Awarded Degree) Session 2010 - 2012 1. Correlation of Mast Cell and Microvascular Density in Carcinoma of Lung by Dr. Ehsan Ullah (Awarded Degree) 2. Smoking Related Interstitial Fibrosis and Interstitial Lung Disease: An Autopsy Study by Dr. Raees Abbas(Awarded Degree) 3. Morphological changes in liver and kidney of rodents induced by indigenous preparation of gold by Dr. Saadia Raza(Awarded Degree) 4. Mercury Kushta induced morphological changes in liver and kidney of rats by Dr. Sakina Jamil (Awarded Degree). Session 2011 -2013 1. Clininopathological Pattern and Classification of Breast Carcinoma based on ER/PR and HER2/ neu Immunohistochemistry by Dr. Farwa Batool(Awarded Degree) 2. Effects of Cadmium Salt on Kidney Tissue of White Rats by Dr. Nasim Aslam (Awarded Degree) Session 2012 - 2014 1. Expression of minichromosome maintenance 2 and Ki-67 as proliferation markers in Renal cell carcinomaby Dr. M. Zain Mehdi(Awarded Degree) 2. Effects of Copper Preparations on Kidneys of Albino Rats by Dr. Hira Kareem (Awarded Degree) 3. Expression of TAMS and M2 Macrophages in Different Histological Grades of Breast Carcinoma by Dr. Nushmia Baig (Awarded Degree). 4. Expression of Isocitrate Dehydrogenase I and internexin alpha in gliomas by Dr. Irfan Basheer (Awarded Degree). Session 2013 - 2015 1. Expression of NGAL in Class I-V Lupus Nephritis Using Immunohistochemical and Immunofluorescent Techniques by Dr. Sobia Khalid (Awarded Degree). 2. Effects of Arsenic Preparations on Kidney and Testes of Wister Rats by Dr. Sadaf Shafique (Awarded Degree). 3. Expression of Ki-67 & P53 as a Prognostic Marker in Wilms� Tumour by Dr. Qurat Ul Ain (Awarded Degree). 4. Detection of DNA Mismatch Repair Antibodies AMS2 MSH6 MSH2 MLH1 in Carcinoma of Breast by Dr. Hadia Rafique (Awarded Degree) Session 2014-16 1. Lead Kushta Induced Morphological Changes in Kidney of Rats by Dr. Rizwan Rasul (M.Phil part 1 exam clearance pending) Session 2015-2017 1. Immunohistochemistry of H. pylori, characterization of its different serological strains and histological grading of chronic gastritis by Dr. Ayesha Suleman (Awarded Degree) 2. Immunohistochemical Expression of Interleukin-30 in Prostate Cancer by Dr. Azka Iqbal (Thesis submitted) 3. Detection of Mycobacterium Tuberculosis in Patients with Lymph Node TB by Immunohistochemistry and Indirect Immunofluorescence Techniques by Wajeeha Arooj (Research in Progress). 4. Detection of Mycobacterium Tuberculosis through Immunocytochemistry & Immunofluorescence from Cervical Lymph node Aspirates by Iqra Ijaz (M.Phil Cytotechnology) (Thesis submitted). 5. Detection of H. Pylori and MLH1 Gene Expression Analysis by Polymerase Chain Reaction in Patients of Chronic Gastritis with and without H.Pylori by Gulam Rasool (Degree Awarded). 6. Detection of Mycobacterium Tuberculosis in Formalin Fixed Parrafin Embedded Tissues through Ziehl-Neelsen Stain and PCR.by Raza Abbas (Degree awarded). 7. Hirschsprung�s Disease and the Role of Calretinin in Rectal Biopsies by Dr. Mishal Sikandar (Awarded Degree). 8. Protective Effect of Ginger on alcohol Induced Steatotic Liver of Rats by Dr. Muhammad Rashid (Awarded Degree). 9. Detection of Helicobacter Pylori through Histochemistryand ImmunofluorescentStaining in Biopsies of Patients with Chronic Gastritis byAsia Rao (Degree Awarded). 10. Comparative determination of integrity of RNA in experimental tissues fixed in formalin, universal molecular fixative and honey by Ayesha Saeed (Project taken over by department). 11. Immunohistochemical Expression and Association of Gata3 with ER Status and Nottingham Grading System of Breast Carcinoma by Dr. Iram Asrar (Degree Awarded). 12. Immunohistochemically Expression of Secreted Protein Acidic and Rich in Cysteine (SPARC) in Biopsies of Patients with Primary Breast Carcinoma of Different Histologic Grades and Clinical Stages by Dr. Waqas Arshad Mughal (Thesis work completed). 13. �Diagnostic Utility of Manual Liquid-based Cytology (MLBC) and Cell Block Preparation in Fine Needle Aspiration Cytology (FNAC) Specimens� by Ahsan Iqbal (Writing Synopsis). 14. Comparative Determination of Integrity of DNA in Experimental Tissues Fixed in Formalin, Universal molecular Fixative and Honey by Nida Ali Ahmed (Thesis writing in progress) Session 2016-2018 Classification of cervical cytological lesions in HIV positive patients according to Bethesda system 2014 by Dr. Sobia Idrak (Thesis work completed) Session 2017-2019 1. Cervical Cytological Changes in Relation with herpes Simplex Virus 1&2 in Pregnant Females of Local Population by Dr. Kainat Farrukh (Thesis Submitted) 2. Expression of Isocitrate Dehydraogenase-! In Gliomas Presenting in Local Population by Dr. Muntaha Masood (Thesis Submitted) 3. Cytological Changes in Relation with Human Papilloma in Patients with Oral Potentially Malignant Lisions by Dr. Maham Javed (Thesis Submitted) 4. Comparative antigenic determination on frozen section by Michel�s Transport medium and direct freezing methods by Mr. Tuaha Amjad ( Synopsis Approved) Session 2018-2020 Cytokeratin 5 Expression on Immunohistochemistry by using Cell Block and Immnocytochemistry by using Liquid Based Cytology by Miss Sumaira Niaz (Thesis writing in progress) Session 2019-2021 1. Dr. Shameen Fatima Shoaib (First Year in Progress) 2. Miss. Gulfishan Zameer (First Year in Progress) 3. Dr. Humaira Javed (First Year in Progress) YEAR WISE ENROLLMENT OF M.PHIL. STUDENTS Year Students� Name Research Title Status Session 2005-2007 Dr. Nadia Naseem Immunohistochemical Expression of Histidine Decarboxylase and Cytokeratin 19 and its correlation with histological grading in primary lung carcinomas � Awarded Degree Session 2006-2008 Dr. Sadia Anwar Expression of HER 2/neu and its correlation with the histological grading of colorectal carcinoma � Awarded Degree Dr. Uzma Nabi Study of Ki-67 labeling index with grading and staging of colorectal carcinoma. � Awarded Degree Dr. Mahwish Hussain Correlation of Estrogen Receptor expression with the Ki-67 proliferative index in carcinoma of the breast � Awarded Degree Dr. Fakeha Rehman Immunohistochemical expression and correlation of Mammaglobin with Scarf-Bloom Richardson grading system of breast carcinoma � Awarded Degree Dr. Seema Butt Expression of Bcl-2 oncoprotein in uterine leiomyomata as an apoptosis inhibitor � Awarded Degree Session 2007-2009 Dr. Sobia Sadiq Diagnostic role of CD117 in small cell carcinoma of lung � Awarded Degree Dr. Saira Sajid A Morphological Study of Muscular Dystrophies and the Role of Dystrophin in their Diagnosis � Awarded Degree Dr. Maham Akhlaq Morphological Study of Placenta in Pre-eclampsia and Eclampsia � Awarded Degree Session 2008-10 Dr. Muneeza Khalid Morphological study of Round Blue Cell Tumors of Childhood and their classification. � Awarded Degree Dr. Nausheen Henna Morphology of Hirschsprung�s Disease in suction and full thickness rectal biopsies � Awarded Degree Session 2009 � 2011 Dr. Munazza Chaudhary Morphology of Hepatitis C Virus Associated Nephropathy and Expression of Anti HCV-NS3 � Awarded Degree Dr. Atika Masood Morphology of IgA &Henoch-Schonlein Nephropathies-the role of immunofluorescence & iNO � Awarded Degree Dr. Usman Shams Expression of p63 and S-100A6 in the Differentiation of KeratinocyticTumours of Skin � Awarded Degree Dr. Sumera Qazi Morphology of Benign Proliferative Breast Lesions in the Mestectomy Specimens. � Awarded Degree Dr. Fatima Rashid Morphological Study of Renal Lesions in Systemic Lupus Erythematosis � Awarded Degree Session 2010 � 2012 Dr. Ehsan Ullah Correlation of Mast Cell and Microvascular Density in Carcinoma of Lung � Awarded Degree Dr. Raees Abbas Smoking Related Interstitial Fibrosis and Interstitial Lung Disease: An Autopsy Study � Awarded Degree Dr. Saadia Raza Morphological changes in liver and kidney of rodents induced by indigenous preparation of gold � Awarded Degree Dr. Sakina Jamil Mercury Kushta induced morphological changes in liver and kidney of rats � Awarded Degree Session 2011 -13 Dr. Farwa Batool Clininopathological Pattern and Classification of Breast Carcinoma based on ER/PR and HER2/ neu Immunohistochemistry � Awarded Degree Dr. Nasim Aslam Effects of Cadmium Salt on Kidney Tissue of White Rats � Awarded Degree Session 2012 � 2014 Dr. M. Zain Mehdi Expression of minichromosome maintenance 2 and Ki-67 as proliferation markers in Renal cell carcinoma � Awarded Degree Dr. Hira Kareem Effects of Copper Preparations on Kidneys of Albino Rats � Awarded Degree Dr. Nushmia Baig Expression of TAMS and M2 Macrophages in Different Histological Grades of Breast Carcinoma � Awarded Degree Dr. Irfan Basheer Expression of Isocitrate Dehydrogenase I and internexin alpha in gliomas � Awarded Degree Session 2013 � 2015 Dr. Sobia Khalid Expression of NGAL in Class I-V Lupus Nephritis Using Immunohistochemical and Immunofluorescent Techniques � Awarded Degree Dr. Sadaf Shafique Effects of Arsenic Preparations on Kidney and Testes of Wister Rats � Awarded Degree Dr. Qurat Ul Ain Expression of Ki-67 & P53 as a Prognostic Marker in Wilms� Tumour � Awarded Degree Dr. Hadia Rafique Detection of DNA Mismatch Repair Antibodies AMS2 MSH6 MSH2 MLH1 in Carcinoma of Breast � Awarded Degree Session 2014-16 Dr. Rizwan Rasul Lead Kushta Induced Morphological Changes in Kidney of Rats � M.Phil. part 1 exam clearance pending Session 2015-17 Dr. Ayesha Suleman Immunohistochemistry of H. pylori, characterization of its different serological strains and histological grading of chronic gastritis � Awarded Degree Dr. Azka Iqbal Immunohistochemical Expression of Interleukin-30 in Prostate Cancer � Thesis submitted Dr. Wajeeha Arooj Detection of Mycobacterium Tuberculosis in Patients with Lymph Node TB by Immunohistochemistry and Indirect Immunofluorescence Techniques � Research in Progress Iqra Ijaz Detection of Mycobacterium Tuberculosis through Immunocytochemistry & Immunofluorescence from Cervical Lymph node Aspirates � M.Phil. Cytotechnology � Thesis submitted Mr. Ghulam Rasool Detection of H. Pylori and MLH1 Gene Expression Analysis by Polymerase Chain Reaction in Patients of Chronic Gastritis with and without H.Pylori � Awarded Degree Dr. Raza Abbas Detection of Mycobacterium Tuberculosis in Formalin Fixed Parrafin Embedded Tissues through Ziehl-Neelsen Stain and PCR � Awarded Degree Dr. Mishal Sikandar Hirschsprung�s Disease and the Role of Calretinin in Rectal Biopsies � Awarded Degree Dr. M Rashid Protective Effect of Ginger on alcohol Induced Steatotic Liver of Rats � Awarded Degree Asia Rao Detection of Helicobacter Pylori through Histochemistry and Immunofluorescent Staining in Biopsies of Patients with Chronic Gastritis � Awarded Degree Ayesha Saeed Comparative determination of integrity of RNA in experimental tissues fixed in formalin, universal molecular fixative and honey � Project taken over by department Dr. Iram Asrar 11. Immunohistochemical Expression and Association of Gata3 with ER Status and Nottingham Grading System of Breast Carcinoma � Awarded Degree Dr. Waqas Arshad Mughal Immunohistochemically Expression of Secreted Protein Acidic and Rich in Cysteine (SPARC) in Biopsies of Patients with Primary Breast Carcinoma of Different Histologic Grades and Clinical Stages � Thesis work completed Ahsan Iqbal �Diagnostic Utility of Manual Liquid-based Cytology (MLBC) and Cell Block Preparation in Fine Needle Aspiration Cytology (FNAC) Specimens� � Writing Synopsis Nida Ali Ahmed Comparative Determination of Integrity of DNA in Experimental Tissues Fixed in Formalin, Universal molecular Fixative and Honey � Thesis writing in progress) Session 2016-18 Dr. Sobia Idrak Classification of cervical cytological lesions in HIV positive patients according to Bethesda system 2014 � Thesis work completed Session 2017-19 Dr. Kainat Farrukh Cervical Cytological Changes in Relation with herpes Simplex Virus 1&2 in Pregnant Females of Local Population � Thesis Submitted Dr. Muntaha Masood Expression of Isocitrate Dehydraogenase-! In Gliomas Presenting in Local Population � Thesis Submitted Dr. Maham Javed Cytological Changes in Relation with Human Papilloma in Patients with Oral Potentially Malignant Lisions � Thesis Submitted Mr. Tuaha Amjad Comparative antigenic determination on frozen section by Michel�s Transport medium and direct freezing methods � Synopsis Approved Session 2018-20 Miss Sumaira Niaz Cytokeratin 5 Expression on Immunohistochemistry by using Cell Block and Immnocytochemistry by using Liquid Based Cytology � Thesis writing in progress Session 2019-21 Dr. Shameen Fatima Shoaib Nill First Year in Progress Miss. Gulfishan Zameer Nill First Year in Progress Dr. Humaira Javed Nill First Year in Progress YEAR WISE ENROLLMENT OF Ph.D STUDENTS Year Students� Name Research Title Status 2004 Dr. Samina Khokher Prediction of Efficacy of Chemotherapy in Breast Cancer-Development of Efficacy Index � Degree Awarded 2006 Dr. Waseem Haider Characterisation of Y-STR in Sexual Assault Victims and Collection of Allele Frequencies and Haplotypes in Punjab � Degree Awarded in 2008 2010 Dr. Nadeem Afzal The Role of Genetics and Immune Mechanisms in the Pathogenesis of Diabetic Retinopathy � Degree Awarded 2010 Dr. Abdul Mannan Babar Surgical Adjuvant Intralesional Cytokines Versus Steriods Hypertrophic Scars and Keloids � Degree Awarded 2011 Dr. Azhar Qayyum Kras Oncogenic Mutation Pattern in Pakistani Patients Presenting with Colorectal Carcinoma in a Northern Tertiary Referral Centre � Degree Awarded in 2016 2012 Dr. Nadia Naseem Immunohistochemical and Genetic characterization of Muscular Dystrophies in Local Population � Degree Awarded in 2016 2013-16 Dr. Usman Shams Role of Epigenetic Regulator EZH2 in Tumorogenesis of Skin � Synopsis approved by ASRB in 2016 under supervision of Prof. AH Nagi and Co-supervision of Dr Saqib Mehmood � Practical Work in progress � Histopathology component is completed while 20% of molecular component of research is to yet to be carried out. Dr. Nausheen Henna Morphological Pattern of Hepatitis B Virus Associated Nephropathy and its Association with Hepatitis B Virus Genotypes � Synopsis approved by ASRB in 2016 under supervision of Prof. AH Nagi and Co-supervision of Dr Saqib Mehmood � Practical Work in progress � Histopathology component is completed while 20% of molecular component of research is to yet to be carried out. 2014-17 Dr. Raees Abbas Expression and Sequencing Analysis of GATA3 gene in local Breast Cancer Population � Working on Research Topic since 2015. � Student was called and emailed to submit draft of synopsis in 2017, 2018, 2019, 2020. However, he hasn�t reported to department about his progress yet. Dr. Farha Bano Niazi Correlation of STIC Positivity in Fallopian Tube with Serous Carcinoma of Ovary and its Relation with BRCA 1 Mutations � Synopsis approved by ASRB in 2017 under supervision of Prof. AH Nagi and Co-supervision of Dr Shah Jahan � Student�s funds will be covered partially by HEC approved project. � Histology and partial molecular components are completed in Histopathology lab and Cell Biology Lab � WB in progress in Cell Biology lab. 2015-18 Dr. Atika Masood Mutations in cancer susceptibility genes and expression of poly ADP-ribose protein in relation to chemotherapy response in patients with surface epithelial ovarian carcinoma � Comprehensive examination passed in 2017. � Synopsis approved by ASRB in 2020 under supervision of Prof Nadia Naseem � Practical work in process Dr. Rahat Sarfraz Analysis of copy number variants and their protein expression in response to treatment in surface epithelial ovarian cancer patients� � Comprehensive examination passed in 2017. � Synopsis approved by ASRB in 2020 under supervision of Prof Nadia Naseem � Practical work in process Dr. Mahvish Hussain � Passed PhD Comprehensive Examination in 2017. � Synopsis writing in progress 2016-19 Dr. Seema Butt � Comprehensive examination failed in 2019. Second attempt awaited. Dr. Bushra Nisar Classification of cervical cytological changes with serological and molecular characterization of sexually transmitted viral infection in females of local population� � Comprehensive examination passed in 2019. � Synopsis approved by ASRB in 2020 under supervision of Prof Nadia Naseem � Practical work in process Co-Supervision (Different Departments): 2014-17 Dr. Kashif Azam (Ph.D oral Pathology) �Identification and characterization of cancer stem cells in head and neck squamous cell carcinoma with and without human papilloma virus� � Synopsis Approved by ASRB under supervision of Prof Nadeem Afzal and Co-supervision of Prof AH Nagi and Dr Shah Jahan. � Student�s funds will be covered partially by HEC approved project. � Sampling & Procurement in Process � Practical work of histology is ongoing in Histopathology lab. 2015-18 Dr. Nauman Rauf Khan mi RNA differential expression analysis in blood plasma of head and necks squamous cell carcinoma patients before and after surgical therapy and HNSCC tissue section with healthy tissue counterpart � Passed PhD Comprehensive Examination in 2017. � Synopsis approved in 2018 � Thesis work in progress 2018-2021 Mr. Ateeq Ashraf Expressional profiling, sequencing analysis and in vitro investigations of CXC chemokine receptors in breast cancer � Passed PhD Comprehensive Examination in 2019. � Synopsis approved in 2020. � Thesis work in progress
